Informazioni sul prodotto
- 1H-Indol-5-ol, 2-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-
- 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
- 2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol
- Pp242
- Torkinib
Torkinib is a matrix-effect inhibitor that inhibits the activity of the mTOR protein. It was initially developed for the treatment of bowel disease, but has been shown to be effective in inhibiting cancer cells as well. Torkinib prevents cell growth by binding to the cytosolic C2 domain and thus preventing activation of cyclic AMP (cAMP). The drug also inhibits hyperproliferative diseases such as psoriasis and cancer by binding to rapamycin and other proteins in an effort to inhibit mTOR activity. Torkinib is used in conjunction with other agents, including rapamycin, for treating cancers such as pancreatic, breast, prostate, colorectal, lung and head and neck cancers. Torkinib may have a more potent effect on cancer cells than on normal cells due to its ability to inhibit the protein polymerase chain reaction (PCR) process. This inhibition prevents DNA replication and protein synthesis from occurring which leads to
Proprietà chimiche
Richiesta tecnica su: 3D-STB35167 Torkinib (PP242)
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