Semaxanib (SU5416)
CAS: 194413-58-6
Rif. 3D-UHA41358
| 1mg | Fuori produzione | ||
| 5mg | Fuori produzione | ||
| 10mg | Fuori produzione | ||
| 25mg | Fuori produzione | ||
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| 500mg | Fuori produzione |
Informazioni sul prodotto
Nome:
Semaxanib (SU5416)
Sinonimi:
- (3Z)-3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
- (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one
- (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one
- (Z)-3-(3,5-Dimethylpyrrol-2-ylmethylene)indolin-2-one
- (Z)-Su 5416
- 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)-
- 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (Z)-
- 3-((2,4-Dimethylpyrrol-5-YL)METHYLIDENYL)-2-indolonone
- 3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)meth-(Z)-ylidene]-2-oxo-2,3-dihydroindole
- Nsc-696819
- Vedi altri sinonimi
- Semaxanib
- Semoxind
- Su-5416
- Sugen
- Tsu-16
Descrizione:
Semaxanib is a small molecule inhibitor of cell signaling pathways that has been shown to inhibit tumor growth in mice with solid tumors. It blocks the activation of the nuclear factor kappa-B (NF-κB) pathway by inhibiting the dephosphorylation and degradation of IκBα, which results in enhanced expression of inflammatory cytokines. Semaxanib also inhibits angiogenesis by blocking the activity of endothelial cell proliferation and migration, as well as tumor cell invasion. The compound also reduces oxidative stress by inhibiting reactive oxygen species production, which contributes to its antitumor effects.
Avviso:
I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Marchio:
Biosynth
Conservazione lunga:
Note:
Proprietà chimiche
Peso molecolare:
238.28 g/mol
Formula:
C15H14N2O
Purezza:
Min. 95%
MDL:
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Codice SA:
