Dilmapimod
CAS: 444606-18-2
Rif. 3D-USA60618
| 1mg | Fuori produzione | ||
| 5mg | Fuori produzione | ||
| 10mg | Fuori produzione | ||
| 25mg | Fuori produzione | ||
| 50mg | Fuori produzione |
Informazioni sul prodotto
- 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[(2-hydroxy-1-hydroxymethylethyl)amino]-8H-pyrido[2,3-d]pyrimidin-7-one
- Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-
- 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
- SB 681323
Dilmapimod is an inhibitor of the enzyme phosphatidylinositol-3-kinase (PI3K) that is involved in the signaling pathway that leads to the release of proinflammatory cytokines. It has been shown to inhibit the production of high-sensitivity C-reactive protein, leukemia inhibitory factor, and interleukin-6, a potent inflammatory mediator. This drug also inhibits the proliferation of pluripotent cells and induces differentiation into cells with a more limited potential. Dilmapimod has been used as a diagnostic tool for identifying patients with autoimmune diseases who have increased levels of high sensitivity c-reactive protein. The drug inhibits tumor necrosis factor alpha (TNFα), which plays a role in chronic inflammation and cancer progression.
