Ent-dorzolamide
CAS: 120279-95-0
Rif. 3D-VEA27995
| 5mg | 248,00 € | ||
| 10mg | 364,00 € | ||
| 25mg | 647,00 € | ||
| 50mg | 925,00 € | ||
| 100mg | 1.392,00 € |
Informazioni sul prodotto
- 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4R,6R)-
- 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4R-trans)-
Ent-dorzolamide is a carbonic anhydrase inhibitor that binds to the β-adrenergic receptor, which is a G protein-coupled receptor. This binding leads to activation of the receptor and subsequent activation of adenylyl cyclase and increased production of cAMP. It has been shown to have insulin sensitizing effects in animal models. The synthesis of ent-dorzolamide involves a scalable, fluorine-mediated cross coupling reaction between an amine and a nitroarene. Ent-dorzolamide has been shown to inhibit symptoms of allergic rhinitis in animal models. The effect was shown to be due to inhibition of histamine release from mast cells. Ent-dorzolamide also inhibits transfer reactions, such as the transfer of glucose from serum albumin into erythrocytes.
Proprietà chimiche
Richiesta tecnica su: 3D-VEA27995 Ent-dorzolamide
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