(+)-CI 1044
CAS: 197894-84-1
Rif. 3D-XHA89484
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Informazioni sul prodotto
- 3-Pyridinecarboxamide, N-(9-amino-3,4,6,7-tetrahydro-4-oxo-1-phenylpyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl)-, (R)-
- 3-Pyridinecarboxamide, N-[(3R)-9-amino-3,4,6,7-tetrahydro-4-oxo-1-phenylpyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]-
- Ci-1044
- N-[(3R)-9-Amino-3,4,6,7-tetrahydro-4-oxo-1-phenylpyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]-3-pyridinecarboxamide
- Pd-189659
(+)-CI 1044 is a peptide that has been shown to activate the G-protein coupled receptor, GlyR. This activation leads to increased levels of intracellular calcium and neurotransmitter release. (+)-CI 1044 is a potent inhibitor of ion channels, especially voltage-gated potassium channels. It also inhibits the activity of peptides that bind to glycine receptors in the central nervous system. The binding site of (+)-CI 1044 is located at the N-terminal segment of the GlyR. The binding site for (+)-CI 1044 has been identified with an antibody by immunoprecipitation and Western blot analysis.
Proprietà chimiche
Richiesta tecnica su: 3D-XHA89484 (+)-CI 1044
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