4Z-P-208018 - pyrrolidine-impurity-4 | 1186426-66-3

Impurity Pregabalin EP impurity A
Applications (S)-Pregabalin Lactam is an impurity of (S)-Pregabalin (P704790) which is a GABA analogue used as an anticonvulsant.
References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999)

Impurity Clemastine EP Impurity A
Applications Clemastine N-Oxide (Clemastine EP Impurity A) is a metabolite of Clemastine Fumarate (C568500); a H1 histamine receptor antagonist and antihistaminic.
References Froehlich, L., et al.: Pharmazie, 51, 409 (1996); Weidmann, et al.: Boll. Chim. Farm., 106, 467 (1967); Gober, B., et al.: Pharmazie, 43, 539 (1988); Breccia, A., et al.: Curr. Ther. Res., 49, 622 (1991); Schran, H., et al.: J. Clin. Pharmacol., 36, 911 (1996)

Applications 3-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-3,4-dihydro-5H-imidazo[2,1-i]purine-5-thione is used in the synthesis of azidoetheno analogs of deoxyadenosine as nucleotide photo-affinity probes.
References Flaherty, D. et al.: Nucleos. Nucleot., 14, 65 (1995);

Applications Hydroxy Velpatasvir is an impurity of antivaral drug Velpatasvir (V116000), which is a HCV NS5A inhibitor used to treat Hepatitis C.
References Feld, J. J., et al.: N. Engl. J. Med. 373, 2599 (2015); Gane, E. J., et al.: Gastroenterol., 151, 448 (2016);