86-MM0336.01-0025 - digitoxigenin | 143-62-4

Digitoxigenin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Digitoxigenin

<p>Digitoxigenin is a precursor of cardiac glycosides that acts by targeting the metastatic uveal melanoma gene signature.</p>

<p>Stability Hygroscopic<br>Applications Digitoxigenin has been used in a study to assess its stereochemical effects in cancer cytotoxicity. It has also been used in a study to investigate the advantage of gold(I)-catalyzed glycosidation of glycosyl o-alkyl benzoates to assemble digitoxin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hinds, J., et al.: Chemmedchem, 8, 63 (2013); Ma, Y., et al.: J. Org. Chem., 76, 9748 (2011)<br></p>

<p>Digitoxigenin is an aglycone, which is a type of steroid structure, derived from the hydrolysis of cardiac glycosides found in plants of the Digitalis species, such as foxglove. This compound is obtained through enzymatic or chemical cleavage of glycosidic bonds present in its parent molecules, digitoxin and others, which are naturally occurring compounds in these plants.</p>

<p>Applications Isotope labelled Digitoxigenin has been used in a study to assess its stereochemical effects in cancer cytotoxicity. It has also been used in a study to investigate the advantage of gold(I)-catalyzed glycosidation of glycosyl o-alkyl benzoates to assemble digitoxin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hinds, J., et al.: Chemmedchem, 8, 63 (2013); Ma, Y., et al.: J. Org. Chem., 76, 9748 (2011)<br></p>