:internalReference - urea | 57-13-6

Urea

Urea, whether or not in aqueous solution

Urea (Carbonyldiamide) is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism.

Urea

<p>Impurity Fluorouracil EP Impurity G<br>Applications Urea (Fluorouracil EP Impurity G) is a physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986), Aebischer, P., et al.: Nat. Med., 2, 696 (1996), Prakash, S., et al.: Biotechnol. Bioeng., 46, 621 (1995),<br></p>

<p>Urea is a natural by-product of protein metabolism in humans, and is also produced commercially from the ammonia by-product of fossil fuel production. Urea is commonly used as a fertilizer, and as a scrubber for removing toxic gases from coal gas, for instance. It can be used in the manufacture of plastics, paints, and explosives. Urea has been shown to have many biochemical properties including its ability to cause cell lysis. This property can be exploited in the laboratory to lyse red blood cells during blood sampling or to lyse bacteria during infectious disease testing. Urea also has an effect on enzyme activities by lowering their pH and increasing their water solubility. The addition of urea to nutrient solutions has been shown to increase slow-release fertilization rates in plants.</p>

UREA CRS