:internalReference - rosuvastatin-ethyl-ester | 851443-04-4
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Rosuvastatin Ethyl Ester
CAS:Formula:C24H32FN3O6SColore e forma:White To Off-White SolidPeso molecolare:509.59Rosuvastatin Ethyl Ester
CAS:Applications Rosuvastatin ethyl ester (CAS# 851443-04-4) is an intermediate formed during the synthetic preparation of rosuvastatin, a pharmaceutical used to manage LDL cholesterol.
References Sterk, D.; et al.: Tetrahedron Lett., 57, 1338 (2016); Olsson, A. G.; et al.: Am. Heart J., 144, 1044 (2002).Formula:C24H32FN3O6SColore e forma:Off-White To Light BeigePeso molecolare:509.59Rosuvastatin Ethyl Ester (Ethyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate)
CAS:Sulfonamides, nesoiFormula:C24H32FN3O6SColore e forma:White PowderPeso molecolare:509.19959Ethyl (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate
CAS:Ethyl (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoatePurezza:99%Peso molecolare:509.6g/molRef: ST-EA-CP-R1020
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaEthyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoate
CAS:Formula:C24H32FN3O6SPurezza:99%Colore e forma:SolidPeso molecolare:509.59087-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(N-methyl-N-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl es ter
CAS:Rosuvastatin is a statin drug that inhibits cholesterol synthesis by inhibiting the enzyme HMG-CoA reductase. Rosuvastatin has been shown to reduce high-sensitivity C-reactive protein (hsCRP) and low-density lipoprotein cholesterol (LDL-C), which are risk factors for cardiovascular disease, in patients with hypercholesterolemia. Rosuvastatin also has a high degree of potency and specificity for the HMG-CoA reductase enzyme and shows no significant cross-reactivity with other HMG-CoA reductase inhibitors. Rosuvastatin is metabolized by CYP3A4 and CYP2C9. Drugs that inhibit these enzymes may increase the plasma levels of rosuvastatin, while drugs that induce these enzymes may decrease the plasma levels of rosuvastatin.Formula:C24H32FN3O6SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:509.59 g/mol
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