AC-22126 - chlorotriisopropylsilane-97 | 13154-24-0

Chlorotriisopropylsilane is used as a silylating agent in neucleotide synthesis. It is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals and in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product port

Tris(isopropyl)silyl chloride

S17950 - triisopropyl chlorosilane

Applications Chlorotris(1-methylethyl)silane is used as a catalyst in the preparation of (silyloxy)cyclobutene derivatives. Also used in the addition of diethylzinc to N-diphenylphosphinoyl imines.
E0
References Sweis, R. et al.: J. Am. Chem. Soc., 126, 7442 (2004); Jimeno, C. et al.: Tetra. Lett., 40, 777 (1999);

Triisopropylchlorosilane is a silylating agent that is used to protect dna duplexes from oxidative damage. It can also be used to inhibit the activity of a number of enzymes, including those involved in metabolic disorders and auto-immune diseases. Triisopropylchlorosilane has been shown to inhibit the production of amyloid protein by stabilizing the complex between the enzyme and its substrate. The compound also inhibits skin cancer cells and has been shown to cause nitrogen atoms in DNA duplexes to bind with oxygen.