AC-40148 - l-asparagine-monohydrate | 5794-13-8

<p>L-Asparagine is a naturally occurring proteinogenic amino acid, used in biomanufacturing cell culture systems for the production of therapeutic recombinant proteins and monoclonal antibodies. It is used in the biosynthesis of proteins. It is also required for development and function of the brain. T</p>

<p>It is used as an isotopically labeled biochemical for proteomics research. It is suitable for all food, beverage and nutritional supplement applications. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information </p>

L-Asparagine monohydrate

<p>L(+)-Asparagine monohydrate</p>

L-Asparagine monohydrate

L(+)-Asparagine monohydrate is a non-essential amino acid, participate in neurological and metabolic regulation of tissue cell function.

<p>Applications L-Asparagine is a naturally occurring amino acid that is not an essential for humans and can be synthesized from central metabolic pathway intermediates.<br>References Burda, P., et al.: Biochim. Biophys. Acta., 1426, 239 (1999); Yamane, H., et al.: Animal. Sci. J., 80, 286 (2009);<br></p>

<p>L-Asparagine monohydrate (LAM) is a water-soluble amino acid that is used in the treatment of metabolic disorders such as diabetes. LAM has been shown to be effective in cell culture and tissue culture experiments, where it was found to increase the production of growth factors, such as insulin and keratinocyte growth factor. This amino acid also has a high degree of kinetic stability and can be used for magnetic resonance spectroscopy studies. LAM is soluble in water, but not in organic solvents. It forms hydrogen bonds with other molecules and is able to form dehydrated crystals. The experimental solubility data for LAM can be found in table 1 below.</p>