AC-41696 - 12266-pentamethylpiperidine-95 | 79-55-0

<p>Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 </p>

1,2,2,6,6-Pentamethylpiperidine

<p>Applications 1,2,2,6,6-Pentamethylpiperidine is used in the synthesis of BN-fused polycyclic aromatic molecules for potential application to electronic materials and apparatus. In addition, it is a catalyst for the chemoselective silylation of benzylic alcohols.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hatakeyama, T. J. Am. Chem. Soc., 133, 18614 (2011); Naiki, M. et al.: Tetrahedron Lett., 42, 5467 (2001);<br></p>