LIGO1 rabbit pAb
Rif. EK-ES11241
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
function:Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.,PTM:N-glycosylated. Contains predominantly high-mannose glycans.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 13 LRR (leucine-rich) repeats.,subunit:Homotetramer. Forms ternary complex with RTN4R/NGFR and RTN4R/TNFRSF19.,tissue specificity:Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients.,
Proprietà chimiche
Richiesta tecnica su: EK-ES11241 LIGO1 rabbit pAb
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