RFX6 rabbit pAb
Rif. EK-ES13408
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.[provided by RefSeq, Sep 2010],
Proprietà chimiche
Richiesta tecnica su: EK-ES13408 RFX6 rabbit pAb
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