DR6 (phospho-Ser562) rabbit pAb
Rif. EK-ES16898
50µl | 188,00 € | ||
100µl | 316,00 € |
Informazioni sul prodotto
- Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)
This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],
Proprietà chimiche
Richiesta tecnica su: EK-ES16898 DR6 (phospho-Ser562) rabbit pAb
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