AMPKβ2 rabbit pAb
Rif. EK-ES20834
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- PRKAB2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],
Proprietà chimiche
Richiesta tecnica su: EK-ES20834 AMPKβ2 rabbit pAb
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