Translin rabbit pAb
Rif. EK-ES3638
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- TSN; Translin; Component 3 of promoter of RISC; C3PO
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012],
Proprietà chimiche
Richiesta tecnica su: EK-ES3638 Translin rabbit pAb
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