MKP-4 rabbit pAb
Rif. EK-ES5033
50µl | 188,00 € | ||
100µl | 316,00 € |
Informazioni sul prodotto
- DUSP9; MKP4; Dual specificity protein phosphatase 9; Mitogen-activated protein kinase phosphatase 4; MAP kinase phosphatase 4; MKP-4
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progr
Proprietà chimiche
Richiesta tecnica su: EK-ES5033 MKP-4 rabbit pAb
Se si desidera richiedere un preventivo o effettuare un ordine, si prega invece di aggiungere i prodotti desiderati al carrello e poi richiedere un preventivo o un ordine dal carrello. È più veloce, più economico, e potrà beneficiare degli sconti disponibili e di altri vantaggi.