E2F-5 rabbit pAb
Rif. EK-ES5038
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- E2F5; Transcription factor E2F5; E2F-5
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 inter
Proprietà chimiche
Richiesta tecnica su: EK-ES5038 E2F-5 rabbit pAb
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