FANCD2 (phospho Ser222) rabbit pAb
Rif. EK-ES5195
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- FANCD2; FACD; Fanconi anemia group D2 protein; Protein FACD2
Fanconi anemia complementation group D2(FANCD2) Homo sapiens The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repai
Proprietà chimiche
Richiesta tecnica su: EK-ES5195 FANCD2 (phospho Ser222) rabbit pAb
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