ABHD4 rabbit pAb
Rif. EK-ES7138
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- ABHD4; Abhydrolase domain-containing protein 4; Alpha/beta-hydrolase 4; Lyso-N-acylphosphatidylethanolamine lipase
caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue.,function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.,similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.,
Proprietà chimiche
Richiesta tecnica su: EK-ES7138 ABHD4 rabbit pAb
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