HDAC3 (phospho Ser424) rabbit pAb
Rif. EK-ES7887
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],
Proprietà chimiche
Richiesta tecnica su: EK-ES7887 HDAC3 (phospho Ser424) rabbit pAb
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