CD35 rabbit pAb
Rif. EK-ES8467
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- complement component (3b/4b) receptor 1/2 (Knops blood group)
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants
Proprietà chimiche
Richiesta tecnica su: EK-ES8467 CD35 rabbit pAb
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