Bob 1 rabbit pAb
Rif. EK-ES8740
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1;BOB-1;OCA-B;OCT-binding factor 1)
disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.,function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the POU2AF1 family.,tissue specificity:B-cell specific.,
Proprietà chimiche
Richiesta tecnica su: EK-ES8740 Bob 1 rabbit pAb
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