PHX2B rabbit pAb
Rif. EK-ES9971
50µl | 188,00 € | ||
100µl | 316,00 € |
Informazioni sul prodotto
paired like homeobox 2b(PHOX2B) Homo sapiens The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016],
Proprietà chimiche
Richiesta tecnica su: EK-ES9971 PHX2B rabbit pAb
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