Cilastatin

CAS: 82009-34-5

Rif. TM-T2583

Informazioni sul prodotto

• Nome: Cilastatin
• Sinonimi: MK0791, (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid, (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid, (2Z)-7-{[(2S)-2-amino-2-carboxyethyl]sulfanyl}-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid, (R-(R*,S*-(Z)))-)Carbonyl)Amino), (Z)-7-[(2S)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid, (z)-(s)-7-Chloro-2-(2,2-Dimethylcyclopropane carboxamido)-2-Heptenoic acid, 2-Heptenoic acid, 7-[(2-amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-, [R-[R*,S*-(Z)]]-, 2-Heptenoic acid, 7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-, (2Z)-, Cilastain, Cilastatin acid, Cilastatine, Cilastatino, Cilastin, Mk-791
• CAS: 82009-34-5

Descrizione

Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.

• Marchio: Targetmol

Proprietà chimiche

• Peso molecolare: 358.45
• Formula: C₁₆H₂₆N₂O₅S
• Purezza: 99.71%
• Colore/Forma: Solid