(S)-Indoximod

CAS: 21339-55-9

Rif. TM-T3S1967

Informazioni sul prodotto

• Nome: (S)-Indoximod
• Sinonimi: N-ME-Tryptophan, Abrine, L-Abrine, (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, 1-Methyl-<span class="text-smallcaps">L</span>-tryptophan, 1-Methyltryptophan, <span class="text-smallcaps">L</span>-(-)-1-Methyltryptophan, <span class="text-smallcaps">L</span>-Tryptophan, 1-methyl-, DL-1-Methyltryptophan, L-(-)-1-Methyltryptophan, L-Tryptophan, 1-methyl-, NSC 77678, Tryptophan, 1-methyl-, <span class="text-smallcaps">L</span>-
• CAS: 21339-55-9

Descrizione

(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, induction of IDO1 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, antitumor activity against mouse LLC cells allografted in C57BL/6 mouse, antiproliferative activity against mouse LLC cells at 50 uM.

• Marchio: Targetmol

Proprietà chimiche

• Peso molecolare: 218.25
• Formula: C₁₂H₁₄N₂O₂
• Purezza: 95.39%
• Colore/Forma: Solid
• InChI: InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)
• InChI key: InChIKey=ZADWXFSZEAPBJS-UHFFFAOYSA-N
• SMILES: Cn1cc(CC(N)C(=O)O)c2ccccc21