Bosentan

CAS: 147536-97-8

Rif. TM-T6264

Informazioni sul prodotto

• Nome: Bosentan
• Sinonimi: Actelion, Ro 47-0203, Benzenesulfonamide, 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2′-bipyrimidin]-4-yl]benzenesulfonamide, 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide, Act 434964, Actelion, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2′-bipyrimidin]-4-yl]-, N-[6-(2-Hydroxyethoxy)-5-(2-Methoxyphenoxy)-2-Pyrimidin-2-Yl-Pyrimidin-4-Yl]-4-Tert-Butyl-Benzenesulfonamide, Ro 47-0203, Ro 47-0203/039, Tracleer, p-tert-Butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide
• CAS: 147536-97-8

Descrizione

Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension.

• Marchio: Targetmol

Proprietà chimiche

• Peso molecolare: 551.614
• Formula: C₂₇H₂₉N₅O₆S
• Purezza: 100%
• Colore/Forma: Pale Yellow To Off-White Solid