Azoniaspironortropanol-d8 Chloride

CAS: 3464-71-9

Rif. TR-A965127

Informazioni sul prodotto

• Nome: Azoniaspironortropanol-d8 Chloride
• Sinonimi: (1R,5S)-2',2',3',3',4',4',5',5'-octadeuteriospiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-ol;chloride, Spiro[8-azoniabicyclo[3.2.1]octane-8,1′-pyrrolidinium], 3-hydroxy-, chloride (1:1), (1α,3β,5α)-, 3-Hydroxyspiro[nortropane-8,1′-pyrrolidinium] chloride, 3α-Hydroxynortropane-8-spiro-1′-pyrrolidinium chloride, Spiro[8-azoniabicyclo[3.2.1]octane-8,1′-pyrrolidinium], 3-hydroxy-, chloride, (1α,3β,5α)-, Spiro[1αH,5αH-nortropane-8,1′-pyrrolidinium], 3α-hydroxy-, chloride

Descrizione

Applications Azoniaspironortropanol-d8 Chloride is the labeled analogue of Azoniaspironortropanol Chloride (A965125), an intermediate used for the synthesis of Trospium Chloride (T892800), an Antispasmodic, used in treatment of urinary incontinence.
References Antweiler, H., et al.: Arzneim.-Forsch., 16, 1581 (1966); Lux, G., et al.: Fortschr. Med., 96, 2113 (1978); Madersbacher, H., et al.: Br. J. Urol., 75, 452 (1995); Zinner, N.R., et al.: Expert Opin. Pharmacother., 6, 1409 (2005)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 225.785
• Formula: C₁₁D₈H₁₂NO·Cl
• Colore/Forma: Neat
• InChI: InChI=1S/C11H20NO.ClH/c13-11-7-9-3-4-10(8-11)12(9)5-1-2-6-12;/h9-11,13H,1-8H2;1H/q+1;/p-1/t9-,10+,11+;/i1D2,2D2,5D2,6D2
• SMILES: [2H]C1([2H])C([2H])([2H])C([2H])([2H])[N+]2([C@H]3CC[C@@H]2C[C@H](O)C3)C1([2H])[2H].[Cl-]