a,a'-Bis[(2-Methoxyphenoxy)methyl]-1,4-piperazinediethanol

CAS: 333749-57-8

Rif. TR-B489850

Informazioni sul prodotto

• Nome: a,a'-Bis[(2-Methoxyphenoxy)methyl]-1,4-piperazinediethanol
• Sinonimi: α1,α4-Bis[(2-methoxyphenoxy)methyl]-1,4-piperazinediethanol
• Marchio: TRC

Descrizione

Applications α,α'-Bis[(2-methoxyphenoxy)methyl]-1,4-piperazinediethanol is a metabolite of Ranolazine (R122500), an anti-ischemic agent which modulates myocardial metabolism. α,α'-Bis[(2-methoxyphenoxy)methyl]-1,4-piperazinediethanol is also known to exhibit anti-anginal activities.
References Aalla, S., et al.: Org. Process. Rsch. Develop., 16, 748 (2012); Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004); McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998); Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002);

Proprietà chimiche

• Peso molecolare: 446.54
• Formula: C₂₄H₃₄N₂O₆
• Colore/Forma: Neat
• InChI: InChI=1S/C24H34N2O6/c1-29-21-7-3-5-9-23(21)31-17-19(27)15-25-11-13-26(14-12-25)16-20(28)18-32-24-10-6-4-8-22(24)30-2/h3-10,19-20,27-28H,11-18H2,1-2H3
• InChI key: InChIKey=SBVOXBJBJCUZFP-UHFFFAOYSA-N
• SMILES: COc1ccccc1OCC(O)CN1CCN(CC(O)COc2ccccc2OC)CC1