3-Bromo-7-nitroindazole

CAS: 74209-34-0

Rif. TR-B686250

Informazioni sul prodotto

• Nome: 3-Bromo-7-nitroindazole
• Sinonimi: 3-bromo-7-nitro-1H-indazole, 1H-Indazole, 3-bromo-7-nitro-, 3-Bromo-7-nitro-1H-indazole, 3-bromo-7-iodo-2H-indazole

Descrizione

Applications 3-Bromo-7-nitroindazole is a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor (1,2). It is also a neuroprotective compound that inhibits the endoplasmic reticulum stress pathway. 3-Bromo-7-nitroindazole has been used to study the role of nitric oxide synthase (nNOS) in spatial memory formation in rats (2).
References (1) Srinivasan, K. and Sharma, S. S.: Life Sci. (2012) 90:154-60(2) Gocmez, S. S., et al.: Pharmacol Biochem Behav. (2015) 131:19-25.

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 242.03
• Formula: C₇H₄BrN₃O₂
• Colore/Forma: Neat
• InChI: InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)
• SMILES: O=[N+]([O-])c1cccc2c(Br)n[nH]c12