N-[4-(2-Bromoethyl)phenyl]methanesulfonamide

CAS: 90485-25-9

Rif. TR-B688124

Informazioni sul prodotto

• Nome: N-[4-(2-Bromoethyl)phenyl]methanesulfonamide
• Marchio: TRC
• Descrizione: Applications N-[4-(2-Bromoethyl)phenyl]methanesulfonamide is an intermediate in the synthesis of Deoxysotalol (D245550) which is the metabolite of Sotalol (S677300), a potent α-adrenergic receptor antagonist and A class III antiarrythmic. Several studies have examined deoxysotalol on its effects on prostaglandin (PGF2a and 15-methyl PGF2α)-evoked contraction using isolated rat uterus and also in potentiating the contractile effects of Oxytocin (O878500).References Uloth, et al.: J. Med. Chem., 9, 88 (1966); Narendranath, K.A., et al.: Euro. J. Pharmacol., 46, 15 (1977); Gautam, C.S., et al., Indian. J. Med. Rsch., 76, 107 (1982)

Proprietà chimiche

• Peso molecolare: 278.17
• Formula: C₉H₁₂BrNO₂S
• Colore/Forma: Neat
• InChI: InChI=1S/C9H12BrNO2S/c1-14(12,13)11-9-4-2-8(3-5-9)6-7-10/h2-5,11H,6-7H2,1H3
• InChI key: InChIKey=PTEMXZYFVMYQKW-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)Nc1ccc(CCBr)cc1