7-(But-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

CAS: 1646355-34-1

Rif. TR-B755315

Informazioni sul prodotto

• Nome: 7-(But-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione
• Sinonimi: 1H-Purine-2,6-dione, 7-(2-butyn-1-yl)-8-(dimethylamino)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]- (ACI), 7-(2-Butyn-1-yl)-8-(dimethylamino)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione (ACI)
• Marchio: TRC
• Descrizione: Applications 7-(But-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione is an impurity of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011)

Proprietà chimiche

• Peso molecolare: 417.464
• Formula: C₂₂H₂₃N₇O₂
• Colore/Forma: White To Off-White
• InChI: InChI=1S/C22H23N7O2/c1-6-7-12-28-18-19(25-21(28)26(3)4)27(5)22(31)29(20(18)30)13-17-23-14(2)15-10-8-9-11-16(15)24-17/h8-11H,12-13H2,1-5H3
• SMILES: CC#CCn1c(N(C)C)nc2c1c(=O)n(Cc1nc(C)c3ccccc3n1)c(=O)n2C