ent-Calindol-13C,d2 Hydrochloride

CAS: 1217619-32-3

Rif. TR-C148707

Informazioni sul prodotto

• Nome: ent-Calindol-13C,d2 Hydrochloride
• Sinonimi: N-[(1S)-1-(1-Naphthalenyl)ethyl]-1H-indole-2-methanamine-13C,d2 Hydrochloride, (S)-2-[[[1-(1-Naphthyl)ethyl]amino]methyl]-1H-indole-13C,d2 Hydrochloride

Descrizione

Applications Labelled (S)-Calindol. A new calcimimetic acting at the calcium sensing receptor; a positive allosteric modulator of the human Ca2+ receptor, activates an extracellular ligand-binding domain-deleted Rhodopsin-like seven-transmembrane structure in the absence of Ca2+.
References Fawzi, A., et al.: Biochemistry, 29, 3804 (1990), Han, G., et al.: J. Biol. Chem., 274, 10008 (1999), Palczewski, K., et al.: Science, 289, 739 (2000), Nemeth, E., et al.: J. Pharmacol. Exp. Ther., 299, 323 (2001), Kew, J., et al.: Pharmacol. Ther., 104, 233 (2004),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 339.86
• Formula: C₂₀₁₃CH₁₉D₂ClN₂
• Colore/Forma: Neat
• InChI: InChI=1S/C21H20N2.ClH/c1-15(19-11-6-9-16-7-2-4-10-20(16)19)22-14-18-13-17-8-3-5-12-21(17)23-18;/h2-13,15,22-23H,14H2,1H3;1H/t15-;/m0./s1/i14+1D2
• InChI key: InChIKey=KFILKQPBQZIRST-XKBPQDPTSA-N
• SMILES: Cl.[2H][13C]([2H])(N[C@@H](C)c1cccc2ccccc12)c1cc2ccccc2[nH]1