21-Carboxy-20-hydroxy-Desonide

CAS: 638-94-8

Rif. TR-C178495

Informazioni sul prodotto

• Nome: 21-Carboxy-20-hydroxy-Desonide
• Sinonimi: (S)-2-Hydroxy-2-((6aR,6bS,7S,8aS,8bR,11aR,12aS,12bS)-7-hydroxy-6a,8a,10,10-tetramethyl-4-oxo-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)acetic Acid, Desonide impurity 1, (11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, 11β,16α,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione 16,17-acetonide, 11β,21-Dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione, 16α,17α-(Isopropylidenedioxy)prednisolone, 16α-Hydroxyprednisolone 16,17-acetonide, 16α-Hydroxyprednisolone 16α,17α-acetonide, 16α-Hydroxyprednisolone acetonide, 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregna-1,4-diene-3,20-dione deriv., Apolar, Budesonide acetonide, D 2083, Desonid, Desonida, Desowen, Locapred, Prednacinolone, Prednacinolone acetonide, Prednisolone acetonide, Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-, Pregna-1,4-diene-3,20-dione, 11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, Prenacid, Sterax, Steroderm, Topifug, Tridesilon, Tridesonit

Descrizione

Applications 21-Carboxy-20-hydroxy-Desonide is an impurity in the synthesis of Desonide (D296940), an anti-inflammatory.
References Phillips, et al.: Toxicol. Appl. Pharmacol., 20, 522 (1971), Sanen, F.J., et al.: Int. J. Clin. Pharmacol. Biopharm., 12, 174 (1975), Tarayre, J.P., et al.: Pharmacol., 19, 323 (1979).

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 432.507
• Formula: C₂₄H₃₂O₇
• Colore/Forma: Neat
• InChI: InChI=1S/C24H32O7/c1-21(2)30-17-10-15-14-6-5-12-9-13(25)7-8-22(12,3)18(14)16(26)11-23(15,4)24(17,31-21)19(27)20(28)29/h7-9,14-19,26-27H,5-6,10-11H2,1-4H3,(H,28,29)/t14-,15-,16-,17+,18+,19?,22-,23-,24-/m0/s1
• InChI key: InChIKey=HUZPDDMMWBKSPS-QOWBJNDQSA-N
• SMILES: CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2([C@H](O)C(=O)O)O1