C6 Ceramide

CAS: 124753-97-5

Rif. TR-C262600

Informazioni sul prodotto

• Nome: C6 Ceramide
• Sinonimi: N-[(E,2R,3S)-1,3-dihydroxyoctadec-4-en-2-yl]hexanamide, Caproyl Ceramide, Ceramide C6, C6 Ceramide Of D-Erythro-C8-Sphingosine, C6-D-Erythro-Ceramide, C8 Sphingoid Base, D-Erythro-Sphingosine, N-Hexanoyl-, 06:0 Ceramide, N-(1,3-dihydroxyoctadec-4-en-2-yl)hexanamide

Descrizione

Applications A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.
References Liu, Z., et al.: J. Neurochem., 106, 2463 (2008), Heakal, Y., et al.: Mol. Cancer Res., 7, 724 (2009), Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009), Mahdy, A., et al.: Mol. Ther., 17, 430 (2009),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 397.63
• Formula: C₂₄H₄₇NO₃
• Colore/Forma: Neat
• InChI: InChI=1S/C24H47NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h18-19,22-23,26-27H,3-17,20-21H2,1-2H3,(H,25,28)/b19-18+/t22-,23+/m1/s1
• InChI key: InChIKey=NPRJSFWNFTXXQC-QFWQFVLDSA-N
• SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCC