Chenodeoxycholic Acid-d5 (Major)

CAS: 52840-12-7

Rif. TR-C291903

Informazioni sul prodotto

• Nome: Chenodeoxycholic Acid-d5 (Major)
• Sinonimi: (3a,5ß,7a)-3,7-Dihydroxycholan-24-oic Acid-d5, (+)-Chenodeoxycholic Acid-d5, 17ß-(1-Methyl-3-carboxypropyl)etiocholane-3a,7a-diol-d5, Chenodeoxycholic Acid-d5, CDC-d5, Chendol-d5, Chenodiol-d5, Chenocol-d5, Fluibil-d5

Descrizione

Applications Labelled Chenodiol (Chenodeoxycholic acid). A major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Fcilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.
References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 397.6
• Formula: C₂₄H₃₅D₅O₄
• Colore/Forma: White To Light Yellow
• InChI: InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1/i8D2,12D2,16D
• InChI key: InChIKey=RUDATBOHQWOJDD-FVAYXOGXSA-N
• SMILES: [2H]C1([2H])C[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@H]4[C@H](C)CCC(=O)O)[C@@H]3[C@H](O)C[C@@H]2C([2H])([2H])[C@]1([2H])O