4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride

CAS: 13815-62-8

Rif. TR-C364430

Informazioni sul prodotto

• Nome: 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride
• Sinonimi: 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Monohydrochloride, p-Chloro-benzoic Acid 1-(p-Methoxyphenyl)hydrazide Monohydrochloride

Descrizione

Applications 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.
References Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 313.18
• Formula: C₁₄H₁₃ClN₂O₂·HCl
• Colore/Forma: Neat
• InChI: InChI=1S/C14H13ClN2O2.ClH/c1-19-13-8-6-12(7-9-13)17(16)14(18)10-2-4-11(15)5-3-10;/h2-9H,16H2,1H3;1H
• InChI key: InChIKey=ANYDSWOBDUWVHE-UHFFFAOYSA-N
• SMILES: COc1ccc(N(N)C(=O)c2ccc(Cl)cc2)cc1.Cl