2-Chloro-10-[3-[[3-(dimethyl-d6-amino)propyl]methylamino]propyl]phenothiazine

CAS: 19077-20-4

Rif. TR-C367112

Informazioni sul prodotto

• Nome: 2-Chloro-10-[3-[[3-(dimethyl-d6-amino)propyl]methylamino]propyl]phenothiazine
• Sinonimi: N-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-N,N',N'-trimethyl-d6-1,3-propanediamine, N1-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-N1,N3,N3-trimethyl-d6-1,3-propanediamine, Chlorpromazine-d6 Impurity B, Chlorpromazine EP impurity B

Descrizione

Applications 2-Chloro-10-[3-[[3-(dimethyl-d6-amino)propyl]methylamino]propyl]phenothiazine is the labeled analogue of 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine (C367110), an impurity of Chlorpromazine (C424750), which is used as an antiemetic; antipsychotic. 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine is also used in the synthesis of novel phenothiazine compounds with antimalarial activity.
References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970); Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990); Kalkanidis, M., et. al.: Biochem. Pharmacol., 63, 833 (2002)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 396.022
• Formula: C₂₁D₆H₂₂ClN₃S
• Colore/Forma: Neat
• InChI: InChI=1S/C21H28ClN3S/c1-23(2)12-6-13-24(3)14-7-15-25-18-8-4-5-9-20(18)26-21-11-10-17(22)16-19(21)25/h4-5,8-11,16H,6-7,12-15H2,1-3H3/i1D3,2D3
• InChI key: InChIKey=TUQCMXWJPGAJBI-WFGJKAKNSA-N
• SMILES: [2H]C([2H])([2H])N(CCCN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc21)C([2H])([2H])[2H]