1-(3-Chloropropoxy)-4-fluorobenzene

CAS: 1716-42-3

Rif. TR-C367680

Informazioni sul prodotto

• Nome: 1-(3-Chloropropoxy)-4-fluorobenzene
• Sinonimi: 3-(4-Fluorophenoxy)propyl chloride, 1-chloro-3-(4-fluorophenoxy)-propane, 1-Chloro-3-(4-fluorophenoxy)propane, 1-Chloro-3-(p-fluorophenoxy)propane, 3-(4-Fluorophenoxy)propylchloride, 3-(p-Fluorophenoxy)propyl chloride, 3-Chloropropyl 4-fluorophenyl ether, 4-(3-Chloropropoxy)-1-fluorobenzene, 4-(3-Chloropropoxy)-4-Fluorobenzene, Benzene, 1-(3-chloropropoxy)-4-fluoro-, Ether, 3-chloropropyl p-fluorophenyl

Descrizione

Applications 1-(3-Chloropropoxy)-4-fluorobenzene was used as a reagent in the preparation of a library of hydantoin compds which has used to study Aurora kinase A inhibitory activity. It was also used as an alkylation agent in the preparation of tetracyclic quinoxaline butyrophenones as 5-HT2A and postsynaptic D2 antagonists and inhibitors of serotonin transporter for treatment of neuropsychiatric and neurological disorders.
References Li, Peng, et al.: J Med. Chem., 57(6), 2670-2682, 2014Bogolubsky, Andrey V., et al.: ACS Comb. Sci., 20(1), 35-43, 2018

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 188.63
• Formula: C₉H₁₀ClFO
• Colore/Forma: Neat
• InChI: InChI=1S/C9H10ClFO/c10-6-1-7-12-9-4-2-8(11)3-5-9/h2-5H,1,6-7H2
• InChI key: InChIKey=DFFWYMMOMUTKOI-UHFFFAOYSA-N
• SMILES: Fc1ccc(OCCCCl)cc1