Cinnabarinic Acid-d4

CAS: 606-59-7

Rif. TR-C442002

Informazioni sul prodotto

• Nome: Cinnabarinic Acid-d4
• Sinonimi: Cinnabarinic-d4 Acid (rings-d4), Cinnavalininic acid-d4, 2-Amino-3-oxo-3H-phenoxazine-4,5,6,7-d4-1,9-dicarboxylic acid, 3H-phenoxazine-1,9-dicarboxylic acid, 2-amino-3-oxo-, Cinnabaric acid, Cinnabarinic acid, Cinnavalininic acid, 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid

Descrizione

Stability Hygroscopic
Applications Cinnabarinic Acid-d4 is the labeled analogue of Cinnabarinic Acid (C442000). which is a natural phenoxazinone derivative, Cinnabarinic acid is obtained in vitro with aid of laccase by oxidative dimerization of 3-Hydroxyanthranilic acid (a metabolite of the amino acid Trytophan). Cinnabarinic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase.
References Osiadacz, J., et al.: J. Biotechnol., 72, 141 (1999), Kumar, D., et al.: Bioorg. Med. Chem., 10, 3997 (2002), McCleland, B., et al.: Bioorg. Med. Chem. Lett., 17, 1713 (2007),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 304.248
• Formula: C₁₄D₄H₄N₂O₆
• Colore/Forma: Neat
• InChI: InChI=1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)/i1D,2D,3D,4D
• InChI key: InChIKey=FSBKJYLVDRVPTK-RHQRLBAQSA-N
• SMILES: [2H]c1c([2H])c([2H])c2oc3c([2H])c(=O)c(N)c(C(=O)O)c-3nc2c1C(=O)O