[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum

CAS: 66845-32-7

Rif. TR-C984525

Informazioni sul prodotto

• Nome: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum
• Sinonimi: (trans-1R,2R-1,2-Diaminocyclohexane)diiodoplatinum, (trans-R,R-1,2-Diaminocyclohexane)diiodoplatinum, (trans-R,R-Cyclohexane-1,2-diamine)diiodoplatinum, Diiodo(trans-l-1,2-cyclohexanediamine)platinum, NSC 290127,(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN,κN']diiodoplatinum, (1R-trans)-1,2-Cyclohexanediamine Platinum Complex, [SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N')diiodoplatinum, USP Oxaliplatin Related Compound
• Marchio: TRC
• Descrizione: Applications [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN')diiodoplatinum is a potential antitumor agent. Impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.References Kidani, Y. et al.: Biomed. Pharmacther., 43, 261 (1989); Noji, M. et al.: J. Med. Chem., 24, 508 (1981); Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),

Proprietà chimiche

• Peso molecolare: 563.08
• Formula: C₆H₁₄I₂N₂Pt
• Colore/Forma: Neat
• InChI: InChI=1S/C6H14N2.2HI.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-6H,1-4,7-8H2;2*1H;/q;;;+2/p-2/t5-,6-;;;/m1.../s1
• InChI key: InChIKey=AEAVNKNQJBFMCW-SKSSAGQDSA-L