trans-1,2-Cyclohexanedicarboxylic Acid

CAS: 2305-32-0

Rif. TR-C984565

Informazioni sul prodotto

• Nome: trans-1,2-Cyclohexanedicarboxylic Acid
• Sinonimi: (1R,2R)-rel-1,2-Cyclohexanedicarboxylic Acid, NSC 31593, (1R,2R)-cyclohexane-1,2-dicarboxylate, (1R,2S)-cyclohexane-1,2-dicarboxylic acid, (1S,2S)-cyclohexane-1,2-dicarboxylic acid, 1,2-Cyclohexanedicarboxylic acid, (1R,2R)-rel-, 1,2-Cyclohexanedicarboxylic acid, trans-, Lurasidone Intermediate(1), Trans-1,2-Cyclohexanedicarboxylicacid, rel-(1R,2R)-1,2-Cyclohexanedicarboxylic acid, trans-1,2-Cyclohexanedicarboxylic acid, trans-Hexahydrophthalic acid

Descrizione

Applications trans-1,2-Cyclohexanedicarboxylic Acid is used as a reagent in the synthesis of enantiopure (α-cyanoalkyl)(tetrahydropyrido[4,3-b]indolecarbonyl)cyclohexanecarboxamides and its analogs as selective cathepsin K inhibitors for the treatment of osteoarthritis. Also used as a reagent in the synthesis of novel cyclopentanedicarboxamide sodium channel blockers as a potential treatment for chronic pain.
References Dossetter, A.G., et al.: J. Med. Chem., 55, 6363 (2012); Shao, P.P., et al.: Bioorg. Med. Chem. Lett., 15, 1901 (2005)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 172.18
• Formula: C₈H₁₂O₄
• Colore/Forma: White
• InChI: InChI=1S/C8H12O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h5-6H,1-4H2,(H,9,10)(H,11,12)/t5-,6-/m1/s1
• InChI key: InChIKey=QSAWQNUELGIYBC-PHDIDXHHSA-N
• SMILES: O=C(O)[C@@H]1CCCC[C@H]1C(=O)O