L-Cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-Tyrosine Trifluoroacetate
CAS:
Rif. TR-C994760
5mg
251,00€
50mg
1.685,00€
Informazioni sul prodotto
Nome:L-Cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-Tyrosine Trifluoroacetate
Prodotto controllato
Sinonimi:
- Linaclotide Linear Trifluoroacetate
Marchio:TRC
Descrizione:Applications L-Cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-Tyrosine is a derivative of Linaclotide (L465880), a guanylate cyclase-C agonist currently being studied in Phase 3 trials for the treatment of irritable bowel syndrome with constipation.References Chey, W.D., et al.: Am. J. Gastroenterol., 107, 1702 (2012); Rao, S., et al.: Am. J. Gastroentrol., 107, 1714 (2012); Brierley, S.M., et al.: Curr. Opinion. Pharmacol., 12, 632 (2012)
Avviso:I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Proprietà chimiche
Peso molecolare:1646.81
Formula:C61H86F3N15O23S6
Colore/Forma:Neat
InChI:InChI=1S/C59H85N15O21S6.C2HF3O2/c1-26(47(82)69-41(25-101)55(90)73-46(27(2)75)57(92)62-19-44(79)64-37(21-97)51(86)68-36(59(94)95)17-29-7-11-31(77)12-8-29)63-56(91)42-4-3-15-74(42)58(93)35(18-43(61)78)67-53(88)39(23-99)72-54(89)40(24-100)71-50(85)34(16-28-5-9-30(76)10-6-28)66-49(84)33(13-14-45(80)81)65-52(87)38(22-98)70-48(83)32(60)20-96;3-2(4,5)1(6)7/h5-12,26-27,32-42,46,75-77,96-101H,3-4,13-25,60H2,1-2H3,(H2,61,78)(H,62,92)(H,63,91)(H,64,79)(H,65,87)(H,66,84)(H,67,88)(H,68,86)(H,69,82)(H,70,83)(H,71,85)(H,72,89)(H,73,90)(H,80,81)(H,94,95);(H,6,7)/t26-,27+,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,46-;/m0./s1
InChI key:InChIKey=STPRSXJEBXBKRW-CPJGTIAWSA-N
SMILES:C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)C(CS)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)C(CCC(=O)O)NC(=O)C(CS)NC(=O)C(N)CS)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O.O=C(O)C(F)(F)F
Richiesta tecnica su: L-Cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-Tyrosine Trifluoroacetate
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