Deacetylvinblastine Hydrazide Sulfate Salt

CAS: 64234-47-5

Rif. TR-D199015

Informazioni sul prodotto

• Nome: Deacetylvinblastine Hydrazide Sulfate Salt
• Sinonimi: O4-Deacetyl-vincaleukoblastin-23-oic Acid Hydrazide Sulfate (salt) (1:1), 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastin-23-oic Acid Deriv., 2H-3,7-Methanoazacycloundecino[5,4-b]indole Vincaleukoblastin-23-oic Acid Deriv., Deacetylvincaleukoblastine Hydrazide Sulfate, Desacetylvinblastine Hydrazide Sulfate
• Marchio: TRC
• Descrizione: Applications Deacetylvinblastine hydrazide sulfate salt is the sulfate salt of Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent that is currently under development as an anti-cancer agent.References Pribble, P. & Edelman, M.: Expert Opin. Invest. Drugs, 21, 755 (2012); Reddy, J., et al.: Cancer Res., 67, 4434 (2007); Roy, M., et al.: Dev. Biol Stand., 74, 323 (1991)

Proprietà chimiche

• Peso molecolare: 867.019
• Formula: C₄₃H₅₆N₆O₇·H₂SO₄
• Colore/Forma: Neat
• InChI: InChI=1S/C43H56N6O7.H2O4S/c1-6-40(53)21-24-22-48(23-40)17-13-26-25-11-8-9-12-29(25)45-34(26)33(35(50)56-5)32(24)27-19-28-30(20-31(27)55-4)47(3)37-42(28)15-18-49-16-10-14-41(7-2,36(42)49)38(51)43(37,54)39(52)46-44;1-5(2,3)4/h8-12,14,19-20,24,32-33,36-38,45,51,53-54H,6-7,13,15-18,21-23,44H2,1-5H3,(H,46,52);(H2,1,2,3,4)/t24-,32+,33+,36+,37-,38-,40+,41-,42-,43+;/m1./s1
• InChI key: InChIKey=SFPPPARDAHXHEV-XBYWVUGMSA-N
• SMILES: CC[C@]1(O)C[C@@H]2C[N@](CCc3c([nH]c4ccccc34)[C@@H](C(=O)OC)[C@@H]2c2cc3c(cc2OC)N(C)[C@H]2[C@@](O)(C(=O)NN)[C@H](O)[C@]4(CC)C=CCN5CC[C@]32[C@@H]54)C1.O=S(=O)(O)O