N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride

CAS: 182808-16-8

Rif. TR-D446953

Informazioni sul prodotto

• Nome: N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride
• Sinonimi: 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxamide

Descrizione

Applications N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 225.383
• Formula: C₉H₉ClN₂O₂
• Colore/Forma: Neat
• InChI: InChI=1S/C9H9ClN2O2/c10-6-3-5(9(12)13)8-4(7(6)11)1-2-14-8/h3H,1-2,11H2,(H2,12,13)
• InChI key: InChIKey=PVXPIJICTUHMAO-WJDAMSDJSA-N
• SMILES: [2H]C([2H])(CCCC(=O)OC)C1([2H])SSCC1([2H])[2H]