Informazioni sul prodotto
Nome:3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone)
Prodotto controllato
Sinonimi:
- 2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one
- 1-Phenyl-3-methyl-1H-4,5-dihydropyrazol-5-one
- 1-Phenyl-3-methyl-2-pyrazolin-5-one
- 1-Phenyl-3-methyl-5-oxopyrazole
- 1-Phenyl-3-methyl-5-pyrazolinone
- 1-Phenyl-3-methyl-5-pyrazolone
- 3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one
- 3-Methyl-1-phenyl-1H-pyrazol-5-one
- 3-Methyl-1-phenyl-2-pyrazolin-5-one
- 3-Methyl-1-phenyl-2-pyrazoline-5-one
- 3-Methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one
- 3-Methyl-1-phenyl-4,5-dihydropyrazol-5-one
- 3-Methyl-1-phenyl-4,5-dihydropyrazole-5-one
- 3-Methyl-1-phenyl-5-pyrazolone
- 3-Methyl-1-phenylpyrazol-5(4H)-one
- 3-Methyl-1-phenylpyrazolin-5-one
- 4,5-Dihydro-3-methyl-5-oxo-1-phenylpyrazole
- 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
- 5-Methyl-2-phenyl-2H-pyrazol-3(4H)-one
- 5-Methyl-2-phenylpyrazol-3-one
- C.I. Developer 1
- Developer Z
- Edarabone
- Edaravone
- Edvaradone
- MCI 186
- Methylphenylpyrazolone
- NCI-C 03952
- NSC 12
- NSC 26139
- NSC 2629
- Norantipyrine
- Norphenazone
- Phenylmethyl pyrazolone
- Radicava
- Radicut,2-Pyrazolin-5-one
- Vedi altri sinonimi
Marchio:TRC
Descrizione:Impurity Phenazone EP Impurity AApplications Edaravone inhibits the disease activity in rheumatoid arthritis. Edaravone can significantly enhance IR flap viability and protect flap vessels, which is related to scavenging oxygen free radicals, reducing the consumption of SOD, reducing the extent of lipid peroxidation and inflammation, and protecting functional structure of vessels in the early stages of reperfusion. It also shows protective effects against STZ-induced cognitive impairment, oxidative stress, cholinergic dysfunction and altered protein expressions. Its acts like a free radical scavenger, decreased apoptotic cell death, oxidative damage to DNA and lipids, and angiogenesis through inhibiting JNK and p38 MAPK pathways in AMD, glaucoma, DR, and RVO animal models.References Reeta KH et al. Eur J Neurosci. 2017 Feb 15Masuda T et al. Oxid Med Cell Longev. 2017;2017:9208489Zhang DY et al. J Huazhong Univ Sci Technolog Med Sci. 2017 Feb;37(1):51-56Criswell LA et al. Am J Med. 2002 Apr 15;112(6):465-71.
Avviso:I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Proprietà chimiche
Peso molecolare:174.20
Formula:C10H10N2O
Colore/Forma:Neat
InChI:InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3
InChI key:InChIKey=QELUYTUMUWHWMC-UHFFFAOYSA-N
SMILES:CC1=NN(c2ccccc2)C(=O)C1
Richiesta tecnica su: 3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone)
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