Emtricitabine N,N’-Methylene Dimer

Rif. TR-E524970

Informazioni sul prodotto

• Nome: Emtricitabine N,N’-Methylene Dimer
• Sinonimi: (R,S)-4,4’-(Methylenebis(azanediyl)bis(5-fluoro-1-((2R,5S)-2-(hyroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
• Marchio: TRC
• Descrizione: Applications Emtricitabine N,N’-Methylene Dimer is a derivative compound of Emtricitabine (E525000), a reverse transcriptase inhibitor. It is effective antiviral agent against HIV, and other viruses replicating in a similiar manner. A nucleoside analog structurally related to Lamivudine (L172500).References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)

Proprietà chimiche

• Peso molecolare: 506.5
• Formula: C₁₇H₂₀F₂N₆O₆S₂
• Colore/Forma: Neat
• InChI: InChI=1S/C17H20F2N6O6S2/c18-8-1-24(10-5-32-12(3-26)30-10)16(28)22-14(8)20-7-21-15-9(19)2-25(17(29)23-15)11-6-33-13(4-27)31-11/h1-2,10-13,26-27H,3-7H2,(H,20,22,28)(H,21,23,29)/t10-,11-,12+,13+/m0/s1
• InChI key: InChIKey=CQCIQUZMNDIBBS-WUHRBBMRSA-N
• SMILES: O=c1nc(NCNc2nc(=O)n([C@@H]3CS[C@H](CO)O3)cc2F)c(F)cn1[C@@H]1CS[C@H](CO)O1