Emtricitabine-13C,15N2

CAS: 1217820-69-3

Rif. TR-E525002

Informazioni sul prodotto

• Nome: Emtricitabine-13C,15N2
• Sinonimi: cis-(+/-)-4-Amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone-(2-13C,1,3-15N2), rel-4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone-(2-13C,1,3-15N2), 2',3'-Dideoxy-5-fluoro-3'-thiacytidine-(2-13C,1,3-15N2), 3'-Thia-2',3'-dideoxy-5-fluorocytidine-(2-13C,1,3-15N2), rac-Emtricitabine-(2-13C,1,3-15N2)

Descrizione

Stability Very Hygroscopic
Applications Labelled Emtricitabine. A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
References Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. Infec. Dis., 182, 599 (2000)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 250.23
• Formula: CC₇H₁₀FN₂NO₃S
• Colore/Forma: White To Light Yellow
• InChI: InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1/i8+1,11+1,12+1
• InChI key: InChIKey=XQSPYNMVSIKCOC-SJLFXUEQSA-N
• SMILES: Nc1[15n][13c](=O)[15n]([C@@H]2CS[C@H](CO)O2)cc1F