Ethyl 3-Aminocrotonate

CAS: 7318-00-5

Rif. TR-E898080

Informazioni sul prodotto

• Nome: Ethyl 3-Aminocrotonate
• Sinonimi: 3-Amino-2-butenoic Acid Ethyl Ester, beta-Aminocrotonic Acid Ethyl Ester, 3-Aminocrotonic Acid Ethyl Ester, Ethyl 3-Amino-2-butenoate, Ethyl beta-Amino-beta-methylacrylate, Ethyl beta-Aminocrotonate, NSC 1086, beta-Aminocrotonic Acid Ethyl Ester
• Marchio: TRC

Descrizione

Applications Ethyl 3-Aminocrotonate is used as a reagent to synthesize Nitrendipine (N490150), a calcium channel antagonist that is used to treat patients with hypertension. Ethyl 3-Aminocrotonate is also used as a reagent to synthesize (S)-Felodipine (F232370), a calcium entry blocker that has antihypertensive properties.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bailey, D., et al.: Clin. Invest. Med., 12, 357 (1989); Bean, B.: Proc. Nat. Acad. Sci., 81, 6388 (1984); Kwon, K., et al.: Tetrahedron, 67, 10222 (2011); Leenen, F. & Holiwell, D.: Am. J. Cardio., 69, 639 (1992); Meyer, H., et al.: Arz. Forsch., 33, 1528 (1983); Stoepel, K., et al.: Arz. Forsch., 31, 2056 (1980)

Proprietà chimiche

• Peso molecolare: 129.16
• Formula: C₆H₁₁NO₂
• Colore/Forma: Neat
• InChI: InChI=1S/C6H11NO2/c1-3-9-6(8)4-5(2)7/h4H,3,7H2,1-2H3/b5-4+
• InChI key: InChIKey=YPMPTULBFPFSEQ-PLNGDYQASA-N
• SMILES: CCOC(=O)/C=C(/C)N